It will wrinkle gundam chrome marker - if you use a chrome paint it will make that dull - and you can't apply paint on top of it.

If you use masking tape on it - it will pull the clear layer right off the paint.

I like it because it's very glossy, it has a self leveling effect even if you get to much on on one spot it evens out. And it works over acrylic, lacquer, and enamel so far (including hardware store paints).